Pentasa Granules, containing mesalamine, are an extended-release formulation specifically designed to treat and prevent flare-ups of mild to moderately active ulcerative colitis in adults. Unlike standard treatments, Pentasa works directly in the intestines, thereby reducing inflammation and easing symptoms such as abdominal pain, diarrhea, and rectal bleeding. Moreover, it is available only by prescription, ensuring safe use under medical supervision (Mayo Clinic).

Key Benefits & Uses

• Helps induce remission in mild to moderately active ulcerative colitis (FDA).

• Assists in maintaining remission and lowering the risk of flare-ups (Drugs.com).

• Offers a granule form for oral administration, which is convenient for daily use (WebMD).

• In addition, it supports long-term management when combined with a healthy lifestyle (WHO).

How to Use

The recommended dosage for adults is 1 gram (four Pentasa 250 mg granules) taken orally four times daily, totaling 4 grams per day (FDA). Furthermore, the granules should be taken with food and swallowed whole, since chewing may reduce effectiveness. Always consult your healthcare provider for personalized dosing instructions. Consequently, this ensures safe and effective treatment tailored to your condition.

Important Safety Information

Before starting Pentasa, your doctor will usually evaluate renal function and continue monitoring it throughout therapy (FDA). In addition, Pentasa should be used cautiously in patients with a history of kidney or gastrointestinal disorders. On the other hand, if any signs of hypersensitivity reactions occur, discontinuation is strongly recommended. Therefore, regular checkups and follow-ups are essential.

Common Side Effects

Like many medications, Pentasa may cause mild to moderate side effects. The most frequently reported include headache, nausea, abdominal pain, diarrhea, and flatulence (Healthline). However, in rare cases, serious issues such as kidney problems or severe allergic reactions may develop. As a result, it is crucial to seek immediate medical advice if unusual symptoms appear.

Why Choose Pentasa Granules

Pentasa provides a targeted treatment approach, since it delivers mesalamine directly to the site of intestinal inflammation. Moreover, its extended-release formulation ensures consistent absorption throughout the digestive tract, which may improve treatment outcomes. Compared to other options, Pentasa offers reliable long-term support in managing ulcerative colitis symptoms. Therefore, patients who require sustained relief often prefer this medication. For more research insights, see PubMed.