Xafinact 50 Tablet contains safinamide and serves as an adjunctive therapy for Parkinson’s disease. It targets “off” episodes in patients who are already on a stable dose of levodopa/carbidopa. Safinamide enhances dopaminergic activity by inhibiting monoamine oxidase B (MAO-B) and modulating glutamate release, thereby improving motor function (mayoclinic.org).

Key Benefits & Uses

Xafinact 50 Tablet provides several advantages:

• Reduces “Off” Episodes: Helps patients regain mobility between levodopa doses.

• Enhances Dopaminergic Activity: Increases dopamine levels for better symptom control.

• Improves Motor Function: Supports smoother and more coordinated movements.

• Adjunctive Therapy: Works effectively alongside levodopa/carbidopa (healthline.com).

How to Use

• Dosage: Start with 50 mg once daily. If tolerated, increase to 100 mg after two weeks.

• Administration: Take tablets orally with or without food. Swallow whole; do not chew or crush.

• Consistency: Take Xafinact at the same time every day to maintain steady drug levels (healthline.com).

Important Safety Information

• Contraindications: Avoid use in patients with severe hepatic impairment or those taking MAO inhibitors.

• Precautions: Adjust dosage for moderate hepatic impairment. Monitor blood pressure regularly.

• Pregnancy & Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding (en.wikipedia.org).

Common Side Effects

Xafinact may cause:

• Involuntary muscle movements, such as twitching.

• Gastrointestinal issues like nausea and diarrhea.

• CNS effects including dizziness, headache, and insomnia.

• Cardiovascular symptoms like elevated blood pressure (drugs.com).

Why Choose Xafinact 50 Tablet

Patients and physicians prefer Xafinact for several reasons:

• Proven Effectiveness: Significantly reduces “off” episodes.

• Dual Mechanism: Combines MAO-B inhibition with glutamate modulation for enhanced symptom management.

• Flexible Dosing: Allows doctors to personalize treatment for optimal outcomes.

• Established Safety Profile: Clinically tested with reliable tolerability (mayoclinic.org).