Crinone Vaginal Gel is a bioadhesive formulation containing micronized progesterone, designed for vaginal administration. It is primarily used to supplement or replace progesterone in women undergoing assisted reproductive technology (ART) procedures, such as in vitro fertilization (IVF), and to treat secondary amenorrhea (absence of menstruation) (Mayo Clinic, Drugs.com).
Key Benefits & Uses:
Crinone provides essential progesterone to support early pregnancy in ART cycles and helps restore menstrual cycles in women with secondary amenorrhea. Its vaginal gel formulation allows for direct absorption, reducing systemic side effects, and offers a non-invasive, convenient alternative to oral medications (FDA, WebMD, Healthline).
How to Use:
Wash hands thoroughly before and after use. Remove the applicator from its pouch and insert it into the vagina as directed by your healthcare provider, usually once or twice daily. Avoid tampons or douches during treatment. Missed doses should be taken as soon as possible unless it is almost time for the next dose (PubMed).
Important Safety Information:
Inform your doctor if you have a history of blood clots, liver disease, breast cancer, or unexplained vaginal bleeding. Allergic reactions such as hives, swelling, or difficulty breathing require immediate medical attention. Use with caution during pregnancy or breastfeeding (WHO).
Common Side Effects:
Mild side effects may include vaginal irritation, breast tenderness, headache, dizziness, or mood changes. Serious symptoms like chest pain, vision changes, or signs of a stroke require urgent medical attention (Drugs.com).
Why Choose Crinone Vaginal Gel:
Crinone’s bioadhesive vaginal gel ensures effective progesterone delivery with convenience and hygiene via single-use applicators. Trusted by healthcare professionals, it is an ideal choice for women seeking fertility support or menstrual regulation (Mayo Clinic, FDA).

