ESTRAVAL Depot Injection is a long-acting intramuscular formulation of estradiol valerate, a synthetic form of the natural estrogen hormone estradiol. It is primarily used in hormone replacement therapy (HRT) for post-menopausal women and in certain medical conditions requiring estrogen supplementation. The medication is also utilized in the management of prostate cancer in men and in gender-affirming hormone therapy for transgender women and non-binary individuals. For more detailed medical references, you can consult Mayo Clinic, Drugs.com, FDA, WebMD, PubMed, Healthline, WHO, and MedlinePlus.

Key Benefits & Uses

ESTRAVAL Depot Injection helps relieve menopausal symptoms such as hot flashes, mood changes, and vaginal dryness. It treats estrogen deficiency due to ovarian failure or hypogonadism, provides palliative therapy for advanced prostate cancer, and supports feminization in gender-affirming therapy. For further information, see Mayo Clinic, WebMD, and Healthline.

How to Use

ESTRAVAL Depot Injection is administered via intramuscular injection by a healthcare professional. Dosage and frequency vary depending on the condition:

• Menopausal symptoms: 10–20 mg every 3–4 weeks

• Prostate cancer: 30 mg or more every 1–2 weeks

• Gender-affirming therapy: 5–20 mg every 2 weeks (up to 30–40 mg as prescribed)

Always follow your healthcare provider’s instructions. For guidance on administration, visit Drugs.com or FDA.

Important Safety

Do not use ESTRAVAL if you have a history of breast or uterine cancer, stroke, heart attack, blood clots, or liver disease. Regular medical monitoring is essential to adjust treatment and reduce risks. For safety information, refer to Mayo Clinic, MedlinePlus, and WHO.

Common Side Effects

Common side effects include headache, breast tenderness, nausea, and mood changes. Serious risks include blood clots, stroke, heart attack, and certain cancers. Contact your healthcare provider if you notice unusual symptoms. For side effect details, consult WebMD or Healthline.

Why Choose ESTRAVAL Depot Injection

ESTRAVAL provides reliable and effective estrogen therapy with a long-acting formulation that ensures stable hormone levels and convenient dosing. It is trusted in clinical settings worldwide. Learn more from FDA and PubMed.