Sirolimus 1 mg tablet is a prescription medication primarily used to prevent organ rejection following kidney transplants. As an immunosuppressant, it works by inhibiting the activation and proliferation of T lymphocytes, which are crucial in the immune response against transplanted organs. Sirolimus is often prescribed alongside other immunosuppressive agents like cyclosporine and corticosteroids to enhance its efficacy in preventing rejection Drugs.com.

Key Benefits & Uses

• Prevention of Organ Rejection: Most commonly used in kidney transplant recipients aged 13 years and older.

• Treatment of Lymphangioleiomyomatosis (LAM): An off-label use for this rare lung disease.

• Combination Therapy: Often used with cyclosporine and corticosteroids for enhanced immunosuppression Drugs.com.

How to Use

• Dosage: The initial dose is typically 6 mg on the first day, followed by 2 mg once daily.

• Administration: Take the tablet whole with a full glass of water.

• Consistency: Take at the same time each day to maintain even blood levels.

• Avoid Grapefruit: Consuming grapefruit or grapefruit juice can increase the risk of side effects Kaiser Permanente.

Important Safety Information

• Allergic Reactions: Seek immediate medical attention if you experience rash, itching, swelling, trouble breathing, or chest tightness.

• Infection Risk: Sirolimus suppresses the immune system, increasing susceptibility to infections.

• Cancer Risk: Long-term use may increase the risk of certain cancers, including lymphoma and skin cancer MedlinePlus.

• Pregnancy Category: May harm an unborn baby; use effective contraception during treatment pfe-pfizercom-prod.s3.amazonaws.com.

Common Side Effects

• Mild: Headache, diarrhea, joint pain, acne, and trouble sleeping.

• Serious: Chest pain, shortness of breath, unusual tiredness, and signs of infection.

• Rare: Progressive multifocal leukoencephalopathy (PML), a serious brain infection Kaiser Permanente.

Why Choose Sirolimus 1 mg Tablet

• Proven Efficacy: Demonstrated effectiveness in preventing kidney transplant rejection.

• Established Safety Profile: Widely studied with a well-understood side effect profile.

• Trusted Brand: Manufactured by reputable pharmaceutical companies, ensuring quality and consistency.