Votrient (pazopanib) is an oral tyrosine kinase inhibitor that treats advanced renal cell carcinoma (RCC) and soft tissue sarcoma (STS) in patients who received prior chemotherapy (FDA). It works by blocking multiple kinases involved in tumor growth and angiogenesis, which helps slow disease progression (Mayo Clinic).
Key Benefits & Uses
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Advanced Renal Cell Carcinoma (RCC): Votrient effectively controls tumor growth in patients with RCC (Drugs.com).
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Advanced Soft Tissue Sarcoma (STS): It provides an effective treatment option for patients with advanced STS after prior chemotherapy (WebMD).
Additionally, Votrient improves patient outcomes by targeting cancer cells directly, while limiting damage to normal cells.
How to Use
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Dosage: Take 800 mg (four 200 mg tablets) once daily, preferably on an empty stomach (FDA).
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Administration: Swallow tablets whole with water; do not crush or chew (Healthline).
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Missed Dose: If you miss a dose, take it as soon as you remember unless the next dose is within 12 hours. Avoid doubling doses.
Regularly following this schedule maximizes treatment effectiveness.
Important Safety Information
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Monitor Liver Function: Votrient may cause severe liver damage. Therefore, doctors recommend frequent liver tests (PubMed).
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Blood Pressure: Monitor regularly because Votrient can raise blood pressure (Mayo Clinic).
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Heart Risks: Patients with prolonged QT interval should use Votrient cautiously (WebMD).
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Drug Interactions: Inform your doctor about all medications, supplements, or herbal remedies you use (WHO).
Common Side Effects
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Gastrointestinal: Diarrhea, nausea, vomiting, decreased appetite.
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Cardiovascular: High blood pressure.
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Skin: Hair and skin color changes.
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General: Fatigue, weight loss.
Consult your healthcare provider if side effects persist or worsen (FDA).
Why Choose Votrient
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Proven Efficacy: Clinical studies show strong results in RCC and STS patients (PubMed).
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FDA Approved: Doctors trust its safety and effectiveness (FDA).
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Targeted Therapy: It directly inhibits cancer-related proteins.
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Convenient: Once-daily oral dosing simplifies treatment.
Thus, Votrient balances effectiveness, safety, and convenience for patients.

