Zenegra 50 mg is a prescription medicine containing sildenafil citrate, widely used for treating erectile dysfunction (ED) in men. It improves blood flow to the penis, allowing natural erections when sexually stimulated. According to the Mayo Clinic, sildenafil is a well-studied therapy for ED and is approved by the FDA for safe and effective use under medical supervision.

Key Benefits & Uses

Zenegra 50 mg offers several benefits:

• Helps men achieve and maintain erections for up to 4–6 hours

• Restores sexual confidence and intimacy

• Sometimes prescribed off-label for pulmonary arterial hypertension and conditions like Raynaud’s phenomenon, with evidence supported by PubMed

• Provides a cost-effective generic alternative to Viagra, containing the same active ingredient (Drugs.com)

How It Works

Sildenafil citrate works by inhibiting the enzyme PDE-5, increasing levels of cGMP in penile tissue. This process relaxes blood vessels and enhances circulation during arousal. As explained by WebMD, the medication only works with sexual stimulation and does not produce an erection on its own.

How to Use

• Take one 50 mg tablet orally with water, ideally 30–60 minutes before sexual activity.

• Effects begin within 30 minutes and may last up to 4 hours (Healthline).

• Avoid fatty meals, alcohol, and grapefruit, which can slow absorption.

• Do not take more than one dose in a 24-hour period.

Important Safety Information

The FDA warns that Zenegra should not be used with nitrates, nitrites, or riociguat due to the risk of severe low blood pressure. People with cardiovascular disease, recent heart attack or stroke, severe liver or kidney problems, or retinal conditions should consult a doctor before use. According to the World Health Organization (WHO), safe ED medication use depends on proper prescription and monitoring.

Common Side Effects

Information from Drugs.com and WebMD indicates that most side effects are mild and temporary, including:

• Headache, flushing, indigestion

• Dizziness, nasal congestion

• Visual disturbances such as blurred or blue-tinted vision

Rare but serious effects include prolonged erections (priapism), sudden vision or hearing loss, which require urgent medical attention.

Why Choose Zenegra 50 mg

• Same active ingredient as Viagra at a lower cost (Mayo Clinic)

• Proven effectiveness in clinical trials reported in PubMed

• Regulated and approved by the FDA and supported under safe prescribing guidelines by the WHO