Tagrisso 80mg tablet is a third-generation targeted therapy used in the treatment of non-small cell lung cancer (NSCLC). Specifically, it helps patients with EGFR gene mutations. Approved in the USA, UK, and Canada, it is widely prescribed for both early-stage and metastatic cases.

Moreover, Tagrisso is known for its ability to overcome resistance caused by T790M mutations, making it a leading choice in modern oncology. Official FDA label for Tagrisso

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💊 Key Indications

Tagrisso is used in the treatment of:

• Metastatic EGFR-mutated NSCLC
• NSCLC with T790M resistance mutation
• Adjuvant therapy after complete tumor resection in early-stage disease

It is suitable for first-line treatment or after disease progression on earlier EGFR inhibitors.

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⚙️ How It Works

Osimertinib, the active ingredient in Tagrisso, binds irreversibly to mutant EGFR receptors, including the T790M mutation, which causes resistance to previous therapies. It specifically targets cancer cells, reducing damage to healthy tissues and offering better tolerability.

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📦 Dosage and Administration

• Standard dose: One 80mg tablet once daily
• Taken orally, with or without food
• Missed a dose? Take as soon as remembered unless close to the next scheduled dose

Patients should follow their oncologist’s guidance on usage.

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⚠️ Common Side Effects

Patients using Tagrisso 80mg tablet may experience:

• Fatigue
• Rash and dry skin
• Diarrhea
• Nail inflammation
• Low white blood cell count

Serious side effects like interstitial lung disease, QT prolongation, or heart complications are rare but possible and require immediate medical attention.

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🌐 Access in USA, UK & Canada

Tagrisso is approved by:

• FDA (USA) for first-line, adjuvant, and post-progression treatment
• NICE (UK) for EGFR-mutated early and advanced NSCLC
• Health Canada, included in provincial drug formularies

Patients can access the drug through hospital pharmacies, specialty cancer centers, or licensed pharmacy providers.

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💰 Affordability and Support

The cost of Tagrisso can be high, but patients in the USA, UK, and Canada can benefit from:

• Manufacturer-sponsored assistance programs
• Insurance reimbursement options
• National health services coverage in the UK and Canada

Speak to a pharmacist or oncologist to explore eligibility and cost-saving support.

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💡 Tips for Patients

• Always confirm EGFR mutation status via genetic testing before treatment
• Avoid grapefruit and CYP3A4 inhibitors (like rifampin, ketoconazole)
• Do not crush or split tablets
• Inform your care team about all medications being taken

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✅ Conclusion

The Tagrisso 80mg tablet is a vital innovation in the fight against EGFR-mutant lung cancer, offering targeted, effective, and life-extending treatment. Approved in major healthcare systems across the USA, UK, and Canada, it’s accessible with support programs and guidance from licensed healthcare providers.

If you or a loved one is managing NSCLC with an EGFR mutation, consult with your oncology specialist or a trusted pharmacy to discuss whether Tagrisso is a suitable treatment.